Biopharm High Capacity PES Cartridge Filters0 pages

BCWPS Cartridge Filters
High Capacity Polyethersulfone Membrane

Applications
Buffers and Feedstocks

SVPs

WFI Water

LVPs

Solvents

Vaccines

Length

5 to 40 in. (12.7 to 101.6 cm) nominal

Outside Diameter

2.75 in. (7.0 cm) nominal

Filtration Area

6.0 ft2 (0.56 m2) per 10 in. length

Integrity Test Information

Representative samples from each manufacturing lot are tested
for integrity to ensure consistent performance.
BCWPS Filters are hydrophilic and manufactured with high
capacity polyethersulfone (PES) membrane. The proprietary
membrane casting process creates a thick membrane with high
contaminant holding capacity, excellent retention characteristics
and high flow rates. Filter elements from each manufacturing
batch are integrity tested during production. BCWPS cartridge
filters are used for critical bioburden reduction applications in
the biopharmaceutical industry. Specific applications for BCWPS
filters are bacteria removal in buffers, USP Water for Injection
(WFI), SVPs, LVPs and other biopharmaceutical solutions.

Maximum Operating Parameters

BCWPS cartridges also see service in removing organic and other
contaminants from wash water and clean in place solutions used
in piping and other systems.

Sanitization/Sterilization

High capacity PES is particularly suited for the filtration of products
that contain elements that can adsorb to the media, such as
preservatives and proteins. The lower binding characteristics
of PES make it a good choice for filtration of valuable protein
solutions such as vaccines and other biopharmaceuticals.

Construction Materials
Filtration Media

High Capacity Polyethersulfone
(PES) Membrane

Media Support

Polypropylene

End Caps

Polypropylene

Center Core

Polypropylene

Outer Support Cage

Polypropylene

Sealing Method

Thermal Bonding

O-rings

Buna, Viton® (or FKM), EP, Silicone,
FEP Encapsulated Silicone, FEP
Encapsulated Viton (or FKM)

Differential Pressure
•t Forward

50 psid (3.4 bard) at 20 °C (68 °F)

•t Reverse

40 psid (2.7 bard) at 20 °C (68 °F)

Operating Temperature
Recommended
Changeout Pressure

82 °C (180 °F) at 10 psid
(0.69 bard) in water
35 psid (2.4 bard)

Filtered Hot Water

90 °C (194 °F), 30 minutes, multiple
cycles, max 3 psid forward flow

Autoclave

121 °C (250 °F), 30 min, multiple cycles

In-line Steam

135 °C (275 °F), 30 min, multiple cycles

For all elevated temperature procedures above, a stainless steel
support ring is required.
Chemical Sanitization
Performed using industry standard concentrations of hydrogen
peroxide, paracetic acid, sodium hypochlorite, and other
selected chemicals.

Total Performance

Critical Process Filtration, Inc. is a vertically integrated manufacturer
of filtration products to industries in which filtration is considered
a critical part of the manufacturing process. We supply a complete
line of products and services to help you cost effectively satisfy all
your filtration requirements from a single source.

Biopharmaceutical Grade

Dimensions