Biomolecule Analysis Using the ICS-5000 Ion Chromatography System0 pages

ICS-5000 Modular, Metal-Free System
Ideal for Bioanalyses
t The ICS-5000 Ion Chromatography
system is the world's first capillary
ion chromatography (IC) system on
the market and provides an impressive
combination of increased productivity,
expanded capabilities, and improved
performance. Modular versatility,
functional integration, and superior
performance culminate in the most
advanced ion chromatography
system available.

The ICS-5000 Reagent-Free™
IC (RFIC™) system is the optimal
liquid chromatography system for
ion-exchange chromatography and
biomolecule analysis. With a 100%
metal-free system (autosampler,
pump, flow path, and detector), the
ICS-5000 system is able to overcome
the limitations of traditional stainless
steel or other metal chromatography
systems affected by corrosive mobile
phases. Metal flow paths can cause
denaturation or absorption effects
with some analytes, resulting in poor
chromatography. Oxidized metals can
poison columns, reducing separation
performance and lifetime. The complete
PEEK™ flow path of the ICS-5000
system, with its ability to resist pH

Passion. Power. Productivity.

values from 1–14, eliminates the
possibility of system corrosion, and
improves robustness. The all-PEEK
pump can also perform quaternary
gradients for demanding application
needs (analytical scale).
The ICS-5000 is the first IC system
to allow separation on the analytical
(4 mm and 2 mm) and capillary
(0.4 mm) scale. Add to this, the ability
to inject small sample volumes (down
to 0.4 µL) from a variety of sample
formats, including well plates; the
versatility of multiple detection schemes
(electrochemical, conductivity, mass
spectrometric [MS] and UV-vis) even
in series; and the ease-of-use of
Always on, Always Ready, makes the
ICS-5000 the most versatile IC system
for bioanalysis.