Sievers 500 RL On-Line TOC Analyzer ? Base Model0 pages

GE Power & Water
Water & Process Technologies

Fact Sheet

Analytical Instruments

Sievers 500 RL
On-Line TOC Analyzer — Base Model
Overview
The Sievers* 500 RL On-Line Total Organic Carbon (TOC)
Analyzer provides continuous monitoring of organics in
ultrapure water for pharmaceutical and power applications. The reagentless 500 RL provides the superior
analytical accuracy and performance found in all
Sievers TOC Analyzers, and offers a range of options
meet specific customer needs.

Features and Benefits
Science-based Design
The Sievers membrane conductometric design eliminates false positive and false negative readings to
which other technologies are susceptible. Additionally,
the Sievers' technology ensures accurate recovery of
all classes of organic compounds commonly found in
UPW waters. In a process capability study comparing
on-line TOC analyzers,1 the Sievers 500 RL was the only
analyzer that demonstrated a meaningful statistical
process capability, making it the only on-line TOC analyzer providing confidence that UPW
processes are fully protected.

European Pharmacopeia (EP) 2.2.44 Total Organic
Carbon, Indian Pharmacopeia (IP) 2.4.30, Chinese
Pharmacopeia (CP) Appendix VIII R, and the Japanese
Pharmacopeia 16 (JP16) 2.59 monographs for Purified
Water and Water for Injection.

Upgrade Options
The 500 RL base model can be configured or upgraded
with a variety of hardware and software options at any
time. Two options are available for introducing calibration and system suitability grab samples: the standard
single-port iOS* (Integrated On-line Sampling System)
and the automated four-port Super iOS.

Ease of Use
The 500 RL is exceptionally easy to
install, operate, and maintain. It
includes a large color touch-screen display, intuitive menu interface, on-screen
consumables status indicators with
maintenance prompts, and advanced
auto-zero features for improved lowlevel performance.

Sievers Super iOS

Pharmaceutical Applications
The Sievers 500 RL is designed to deliver sciencebased risk management capability to the production
floor. It provides reagentless on-line TOC analysis for
compliance with US Pharmacopeia (USP) <643>,

In addition to the Super iOS, options
specifically for pharmaceutical customers include USP Chapter <645> conductivity measurement, automated USP
system suitability, linearity functionality,
and Sievers DataGuard* for facilitating 21
CFR Part 11 compliance. The optional
DataShare* 500 enables all customers to
view, share and create reports from the
500 RL’s encrypted data USB output.

Technical Support and Services
GE Analytical Instruments provides ongoing technical
support, as well as on-site installation, maintenance,
calibration, and training services that together assure
optimal performance from Sievers instruments. For
more information, visit www.geinstruments.com.