Thermoanalytical Characterization of Pharmaceuticals0 pages

Thermoanalytical Characterization of Pharmaceuticals
NETZSCH Annual 2000

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The NETZSCH Annual 2000 Thermoanalytical Characterization of Pharmaceuticals
(engl.) is based on decades of experience of the renowned specialists Dr. E. Marti,
Solvias AG (former Novartis), Basle / Switzerland, and Prof. Dr. W.-Y. Ma, Shanghai
Institute of Pharmaceutical Industry, Shanghai / P.R.C., in the fields of Pharmaceutical Research and Technology, as well as E. Kaisersberger and Dr. G. Kaiser, NETZSCH
“Thermal Analysis Applications”, NETZSCH-Gerätebau GmbH, Selb / Germany.

Annual 2000

Thermoanalytical Characterization
of Pharmaceuticals

Selected examples of drug substances and excipients are outlined in this workbook, which is based on thermoanalytical measurements using DSC, thermobalance, TG-FTIR, TG-DSC-MS and c-DTA.
Each substance is introduced by literature data and pharmaceutical use. Special
attention having been paid to the presentation of easily understandable
experimental results.
In addition, the collected experimental facts have been evaluated by different
software programs. Routines have been applied for the determination of melting
points, enthalpy of fusion and crystallization, dehydration, purity, kinetic data,
Gibbs free energy function, melting range and molten fraction. The importance of
gas analysis by FTIR and mass spectrometry has been underlined.
The results obtained with the performed investigations are brought into the
context of thermodynamics, physical chemistry and solid-state or material sciences.

E. Marti • E. Kaisersberger • G. Kaiser • W.-Y. Ma

Authors
E.Marti
E. Kaisersberger
G. Kaiser
W.-Y. Ma

Below you can have a look at the table of contents.

NETZSCH-Gerätebau GmbH
Wittelsbacherstraße 42
95100 Selb
Germany
Tel.: t+49 9287 881-0
Fax: t+49 9287 881 505
at@netzsch.com
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