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Biopharm High-Capacity PES Capsules0 pages
BCWPS Capsule Filters
High Capacity PES Membrane
Applications
Buffers and Feedstocks
SVPs
WFI Water
LVPs
Solvents
Vaccines
BCWPS capsule filters are used for bioburden reduction
applications in the biopharmaceutical industry. Applications
for BCWPS capsule filters include bacteria removal in buffers,
USP Water for Injection (WFI), SVPs, LVPs and other products.
Filter elements from each manufacturing lot are integrity tested
during production. BCWPS capsules also see service in removing
organic and other contaminants from wash water and clean in
place solutions used in piping and other systems.
Excellent flow rates with excellent retention
characteristics
Remove organic contaminants from liquid streams
P
rotect processes by removing organic contaminants
from wash water, CIP solutions
High capacity polyethersulfone is particularly suited for the
filtration of products that contain elements that can adsorb to
media, such as preservatives and proteins. The lower binding
characteristics of PES make it a good choice for filtration of valuable
protein solutions such as vaccines and other biotech products.
Low product adsorption for protein solutions
BCWPS Capsule Filters - Filtration Area
Capsule Length
Media
High Capacity PES
Membrane
2”
5”
1.0 ft (930cm )
2
2
10”
3.0 ft (2788cm )
2
20”
6.0 ft (5574cm )
2
2
2
30”
12.0 ft (11148cm ) 18.0 ft (16722cm2)
2
2
2
Flow Rate / Filtration Area
The following table represents typical water flow at a one psi (69 mbar) pressure differential across a single 2 inch capsule with 0.9 ft²
(836 cm²) of media with 1/2” FNPT ports. The test fluid is water at ambient temperature. Higher pressure drops are acceptable, but as
flows increase the pressure drop of the housing becomes more apparent.
0.22 μm
0.45 μm
0.65 μm
1.2 μm
GPM
0.18
0.21
0.68
1.05
LPM
0.68
0.79
2.57
3.97
Pore Size
* For approximate flow rates for 5” through 30” capsules, refer to the appropriate cartridge data sheet
Construction Materials
Maximum Operating Parameters
Polypropylene
Liquid Operational Pressure
Filtration Media
High Capacity Polyethersulfone
(PES) Membrane
Gases Operational Pressure
60 psi (4.1 bar) at 20 °C (68 °F)
Operating Temperature
Media Support
Polypropylene
43 °C (110 °F) at 30 psi
(2.1 bar) in water
End Caps
Polypropylene
Forward Differential Pressure 50 psid (3.4 bard) at 20 °C (68 °F)
Center Core
Polypropylene
Reverse Differential Pressure
40 psid (2.7 bard) at 20 °C (68 °F)
Outer Support Cage
Polypropylene
Sealing Method
Thermal Bonding
Recommended Changeout
Pressure
35 psid (2.4 bard)
Housing
80 psi (5.5 bar) at 20 °C (68 °F)
Biological Grade
BCWPS capsule filters are hydrophilic and manufactured with
high capacity polyethersulfone membrane. The proprietary
membrane casting process creates a thick membrane with high
contaminant holding capacity, excellent retention characteristics
and high flow rates.
