Biopharm High Capacity PVDF Cartridge Filters0 pages

BPVWL Cartridge Filters
High Capacity PVDF Membrane

Applications
SVPs

WFI Water

LVPs

Serum

Vaccines

Plasma Products

Dimensions
Length

5 to 40 in. (12.7 to 101.6 cm) nominal

Outside Diameter

2.75 in. (7.0 cm) nominal

Integrity Test Information

Representative samples from each manufacturing lot are tested
for integrity to ensure consistent performance.
Biopharmaceutical grade PVWL filters are made using hydrophilic
polyvinylidene fluoride (PVDF) membrane. The proprietary
membrane casting process creates a thick membrane with
excellent retention characteristics and flow rates and low protein
binding. BPVWL cartridges are used for a wide range of critical
applications in the biopharmaceutical production.
Applications include bioburden reduction in buffers and media,
water for injection (WFI), solvents, alcohols and other liquids. Our
filters provide high efficiency, validatable performance protecting
sterilizing grade filters.
PVDF is particularly suited for the filtration of products containing
elements that can adsorb to the media, such as preservatives and
proteins. The very low binding nature of PVDF makes it a good
choice for filtration of valuable protein solutions such as vaccines,
plasma products, MAb products, other biopharmaceuticals as
well as products that contain low amounts of preservatives.

Construction Materials
Filtration Media

High Capacity Polyvinylidene
Fluoride (PVDF) Membrane

Media Support

Polypropylene

End Caps

Polypropylene

Center Core

Polypropylene

Outer Support Cage

Polypropylene

Sealing Method

Thermal Bonding

O-rings

Buna, Viton® (or FKM), EP, Silicone,
FEP Encapsulated Silicone, FEP
Encapsulated Viton (or FKM)

Maximum Operating Parameters
Differential Pressure
•t Forward

50 psid (3.4 bard) at 20 °C (68 °F)

•t Reverse

40 psid (2.7 bard) at 20 °C (68 °F)

Operating Temperature
Recommended
Changeout Pressure

82 °C (180 °F) at 10 psid
(0.69 bard) in water
35 psid (2.4 bard)

Sanitization/Sterilization
Filtered Hot Water

90 °C (194 °F), 30 minutes, multiple
cycles, max 3 psid forward flow

Autoclave

121 °C (250 °F), 30 min, multiple cycles

In-line Steam

135 °C (275 °F), 30 min, multiple cycles

For all elevated temperature procedures above, a stainless steel
support ring is required.
Chemical Sanitization
Performed using industry standard concentrations of hydrogen
peroxide, paracetic acid, sodium hypochlorite, and other
selected chemicals.

Total Performance

Critical Process Filtration, Inc. is a vertically integrated
manufacturer of filtration products to industries in which
filtration is considered a critical part of the manufacturing
process. We supply a complete line of products and services to
help you cost effectively satisfy all your filtration requirements
from a single source.

Biopharmaceutical Grade

Buffers and Feedstocks